Thyroid cancer is the most frequent endocrine malignancy, and its incidence and prevalence are increasing worldwide. Despite its\ngenerally good prognosis, the observedmortality rates are higher in the less-developed regions. This indicates that timely diagnosis\nand appropriate initial management of this disease are important to achieve a positive outcome. We performed an observational\nstudy in order to describe the frequency of the BRAF 1799T>A mutation in Mexican mestizo patients with thyroid nodules, a\nscarcely studied ethnic group with large populations. Competitive allele-specific Taqman PCR was performed in 147 samples\nof thyroid tissue DNA obtained from patients histologically diagnosed with papillary thyroid cancer (PTC), colloid goiters, and\nfollicular adenomas. The BRAF 1799T>A mutation frequency was 61.1% in PTC samples (
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